Publications and presentations

Publications

Linna M, Vuoti S, Silander K, Hörhammer I, Halminen O, Mikkola T, Koivuranta-Vaara P, Virta L, Koivusalo M, Ylisaukko-oja T: Impact of Anti-Dementia Medication on the Risk of Death and Causes of Death in Alzheimer’s Disease. Journal of Alzheimer’s Disease, vol. Pre-press, no. Pre-press, pp. 1-12, 2019.

Hynninen Yrjänä, Linna Miika, Vilkkumaa Eeva (2019). Value of genetic testing in the prevention of coronary heart disease events. PLoS ONE 14(1):e0210010.

Intelligent Patient Flow Management System at a Primary Healthcare Center-The Effect on Service Use and CostsTenhunen, H., Hirvonen, P., Linna, M., Halminen, O., & Hörhammer, I. (2018). In Decision Support Systems and Education: Help and Support in Healthcare (pp. 142-146). (Studies in Health Technology and Informatics; Vol. 255).

Hörhammer, Iiris, Linna, Miika ja Oksman, E. (2018). 8-Year Follow-up of a Health Coaching Intervention Effects on Health and Social Care Service Use, Cost of Care and Clinical Endpoints. World Congress of Cardiology & Cardiovascular Health, Dubai, Yhdistyneet Arabiemiraatit

Linna, M., Vuoti, S., Silander, K., Hörhammer, I.Halminen, O., Mikkola, T., Koivuranta-Vaara, P., Virta, L. J., Koivusalo, M. & Ylisaukko-Oja, T., Impact of Anti-Dementia Medication on the Risk of Death and Causes of Death in Alzheimer’s Disease1 Jan 2019In : Journal of Alzheimer’s Disease. 714p. 1297-1308 12 p.

Hiltunen A, Hörhammer I, Silander K, Laukkanen J , Linna M. Integrating health service delivery for geriatric patients after hospital admission – A register study on the outcomes and costs. Health Service Management Research 2019. published online: November 26, 2019.

Oksman E, Hörhammer I,  Absetz P, Patja K, Lammintakanen J, Talja M, Kuronen R, Linna M. Eight-year post-trial follow-up of health care and long-term care costs of tele-based health coaching. Health Services Research 2019. In press.

Electronic health records as valuable data sources in health care quality improvement process. Wikström K, Toivakka M, Rautianen P, Tirkkonen H, Repo T, Laatikainen T: Health Services Research & Managerial Epidemiology, 2019.

Outcomes of Secondary Prevention among Coronary Heart Disease Patients in a High-Risk Region in Finland. Teppo Repo, Markku Tykkyläinen, Juha Mustonen, Tuomas T. Rissanen, Matti Ketonen, Maija Toivakka, Tiina Laatikainen. Environ. Res. Public Health 2018.

Akter Nazu Nazma, Lindström Jaana, Rautiainen Päivi, Tirkkonen, Hilkka, Wikström Katja, Repo Teppo, Laatikainen Tiina. Maintenance of good glycaemic control is challenging – A cohort study of type 2 diabetes patient in North Karelia Finland. Int J Clin Pract. 2019 Jan 21:e13313.

Iiris Hörhammer, Juulia Jäppinen, Miika Linna: Healthcare Professionals’ Expectations of a Diabetes Care Performance Management System. MedInfo 2019: 1680-1681

Nazu NA, Wikström K, Lamidi ML, Lindström J, Tirkkonen H, Rautiainen P, Laatikainen T. Association of mental disorders and quality of diabetes care – A six-year follow-up study of type 2 diabetes patients in North Karelia, Finland. Diabetes Res Clin Pract  2020. 

Treatment lines and glycemic control among patients with type 2 diabetes in North Karelia, Finland. Nallely Ramirez Solano, Master’s thesis (2020). University of Eastern Finland.

Wikström K, , Lamidi ML, Rautiainen P, Tirkkonen H, Kivinen P, Laatikainen T. The effect of the integration of health services on health care usage among patients with type 2 diabetes in North Karelia, Finland. BMC Health Serv Res. 2021 Jan 13;21(1):65.

Lamidi ML, Wikström K, Inglin L, Rautiainen P, Tirkkonen H, Laatikainen T. Trends in the process and outcome indicators of type 2 diabetes care: a cohort studyfrom Eastern Finland, 2012-2017. BMC Fam Pract 2020 Dec 4;21(1):253.

Inglin L, Lavikainen P, Jalkanen K; Laatikainen T. LDL-cholesterol trajectories and statin treatment in Finnish type 2 diabetes patients: A growth mixture model. Sci Rep 11, 22603 (2021).

Pyykönen M, Linna M, Tykkyläinen M, Delmelle E, Laatikainen T. Patient-specific and healthcare real-world costs of atrial fibrillation in individuals treated with direct oral anticoagulant agents or warfarin. BMC Health Services Research 2021;21(1):1299.

Carinci F, Štotl I, Cunningham S, Poljicanin T, Pristas I, Traynor V, Olympios G, Scoutellas V, Azzopardi J, Doggen K, Sándor J, Adany R, Løvaas K, Jarosz-Chobot P, Polanska J, Pruna S, de Lusignan S, Monesi M, Di Bartolo P, Scheidt-Nave CE, Heidemann C, Zucker I, Maurina A, Lepiksone J, Rossing P, Arffman M, Keskimäki I, Gudbjornsdottir S, Di Iorio CT, Dupont E, de Sabata S, Klazinga N, Massi Benedetti M. Making use of comparable health data to improve quality of care and outcomes in diabetes: the EUBIROD review of diabetes registries and data sources in Europe. Frontiers in Clinical Diabetes and Healthcare (Diabetes Clinical Epidemiology) 2021.

Erja Mustonen, Iiris Hörhammer , Kristiina Patja , Pilvikki Absetz , Johanna Lammintakanen , Martti Talja , Risto Kuronen and Miika Linna. Eight-year post-trial follow-up of morbidity and mortality of telephone health coaching. BMC Health Services Research (2021).

Kristiina Manderbacka, Markku Satokangas, Martti Arfman, Eeva Reissell, Ilmo Keskimäki, ja Alastair H. Leyland. Explaining regional variation in elective hip and knee arthroplasties in Finland 2010−2017—a register-based cohort study. BMC Health Services Research (2022).

Wikström K, Lamidi M-L, Rautiainen P, Tirkkonen H, Laatikainen T. Type 2 diabetes medication and HbA1c levels in North Karelia Finland, 20132019. Diabet Med. 2022.

Inglin L, Wikström K, Lamidi ML, Laatikainen T. The adverse effect of the COVID-19 pandemic on health service usage among patients with type 2 diabetes in North Karelia, Finland. BMC Health Serv Res. 2022.

Nazu NA, Wikström K, Lamidi ML, Lindström J, Tirkkonen H, Rautiainen P, Laatikainen T. Mode of treatments and achievement of treatment targets among type 2 diabetes patients with different comorbidities a register-based retrospective cohort study in Finland. BMC Prim Care. 2022 Nov 9;23(1):278.

Wikström K, Linna M, Laatikainen T. The impact of the COVID-19 pandemic on incident cases of chronic diseases in Finland. Eur J Public Health. 2022 Aug 16:ckac107.

Lavikainen P, Lamidi ML, Repo T, Inglin L, Martikainen J, Laatikainen T. Effects of COVID-19 Pandemic and Lockdown on Monitoring and Treatment Balance of Finnish Coronary Heart Disease and Type 2 Diabetes Patients. Clinical Epidemiology 2022; 14:1363-73.

Mustonen J, Rautiainen P, Lamidi M-L, Lavikainen P, Martikainen J, Laatikainen T. Marked Improvement in A1C Levels After Initiation of Intermittently Scanned Continuous Glucose Monitoring is Maintained over 4 Years in Patients with Type 1 Diabetes. Diabetes Spectrum 2022; doi:10.2337/ds21-0087.

Lavikainen P, Aarnio E, Linna M, Jalkanen K, Tirkkonen H, Rautiainen P, Laatikainen T, Martikainen J. Data-driven long-term glycaemic control trajectories and their associated health and economic outcomes in Finnish patients with incident type 2 diabetes. PONE 2022.

Martiskainen T, Lamidi M-L, Venojärvi M, Tikkanen H, Laatikainen T. Effectiveness of physical activity counselling provided for people with type 2 diabetes mellitus in primary healthcare in North Karelia, Finland: a register-based evaluation study. BMJ Open 2022.

Satokangas M, Lumme S, Arffman M, Keskimäki I: Trajectory modelling of ambulatory care sensitive conditions in Finland in 1996–2013: assessing the development of equity in primary health care through clustering of geographic areas – an observational retrospective study. BMC Health Services Research 2019, 19(1):629.

Manderbacka K, Arffman M, Satokangas M, Keskimäki I: Regional variation of avoidable hospitalisations in a universal health care system: a register-based cohort study from Finland 1996−2013. BMJ Open 2019, 9(7):e029592.

Keskimaki, I, Tynkkynen, L-K, L Reissell, E, Koivusalo, M, Syrja, V, Vuorenkoski, L, Rechel, B, Karanikolos, M. (2019). Finland: Health System Review. Health systems in transition. 21. WHO, 1-166.

Partanen V-M, Arffman M, Manderbacka K, Keskimäki I. (2020) Mortality related to ambulatory care sensitive hospitalisations in Finland. Scandinavian Journal of Public Health.

S Lumme, K Manderbacka, M Arffman, S Karvonen and I Keskimaki. Cumulative social disadvantage and hospitalisations due to ambulatory care-sensitive conditions in Finland in 2011-2013: a register study. BMJ Open 2020

Satokangas, M., Arffman, M., Antikainen, H., Leyland, A. H., & Keskimäki, I. (2021). Individual and Area-level Factors Contributing to the Geographic Variation in Ambulatory Care Sensitive Conditions in Finland: A Register-based Study. Medical care, 59(2), 123-130.

Vikstedt T, Arffman M, Heliövaara-Peippo S, Manderbacka K, Reissell E, Keskimäki I. Change in medical practice over time? A register based study of regional trends in hysterectomy in Finland in 2001-2018. BMC Women’s Health 2021;21:242

Satokangas, M. Geographic equity in primary health care performance in Finland – from individual socioeconomic position into the blind spot of the service system. Artikkeliväitöskirja, Helsingin yliopisto.

Marcos R Martines, Ricardo Vicente Ferreira, Rogério Hartung Toppa, LM Assunção, Michael R Desjardins, Eric M Delmelle (2021). Detecting space–time clusters of COVID-19 in Brazil: mortality, inequality, socioeconomic vulnerability, and the relative risk of the disease in Brazilian municipalities. Journal of Geographical Systems23 (1), 7–36.

The usefulness of small-area-based socioeconomic characteristics in assessing the treatment outcomes of type 2 diabetes patients: a register-based mixed-effect study. Toivakka Maija, Pihlapuro Aki, Tykkyläinen Markku, Mehtätalo Lauri, Laatikainen Tiina. BMC Public Health 2018.

Self-monitoring induced savings on type 2 diabetes patients’ travel and healthcare costs. Aapeli Leminen, Markku Tykkyläinen, Tiina Laatikainen. International Journal of Medical Informatics, Volume 115, 2018.

Pyykönen M, Leminen A, Tynkkynen J, Tykkyläinen M & Laatikainen T. A geospatial model to determine the spatial cost-efficiency of anticoagulation drug therapy: patients’ perspective. Geospatial Health 2019;14(809): 265-274.

Leminen A, Pyykönen M, Tynkkynen J, Tykkyläinen M & Laatikainen T. Modeling patients’ time, travel, and monitoring costs in anticoagulation management: societal savings achievable with the shift from warfarin to direct oralanticoagulants. BMC Health Services Research  2019;19(901): 1-13.

Huotari T, Rusanen J, Keistinen T, Lähderanta T, Ruha L, Sillanpää MJ & Antikainen H. (2020) Effect of centralization on Geographic accessibility of maternity hospitals in Finland. BMC Health Services Research 2020; 20(337): 1-9.

Geospatial variations in quality of type 2 diabetes care. Evidence from electronic health records in North Karelia, Finland. Maija Toivakka, doctoral thesis (2020). University of Eastern Finland.

Kotavaara, O., Nivala, A., Lankila, T., Huotari, T., Delmelle, E. & Antikainen, H. (2021). Geographical accessibility to primary health care in Finland – Grid-based multimodal assesment. Applied Geography 136, 102583.

Mariescu-Istodor R & Fränti P (2021): Fast travel-distance estimation using overhead graph, Journal of Location Based Services.

Sieranoja S & Fränti P (2021): Adapting k-means for graph clustering, Knowledge and Information Systems.

Eric Delmelle, Michael R. Desjardins, Paul Jung, Claudio Owusu, Yu Lan, Alexander Hohl, Coline Dony (2021). Uncertainty in Geospatial Health: Challenges and Opportunities Ahead, Annals of Epidemiology.

Jan Ebert, Kramer Michael, Eric Delmelle and Russ Kirby (2021). What is the place for space in epidemiology? Annals of Epidemiology.

Fränti P, Sieranoja S, Wikström K, Laatikainen T. Clustering Diagnoses From 58 Million Patient Visits in Finland Between 2015 and 2018. JMIR Med Inform. 2022 May 4;10(5):e35422.

Rautiainen E, Ryynänen O-P, Laatikainen T & Kekolahti P: Factors Associated with 5-Year Costs of Care among a Cohort of Alcohol Use Disorder Patients: A Bayesian Network Model. Healthcare Informatics Research 2020;26(2):129-145.

Rautiainen E, Linna M, Ryynänen O-P, Laatikainen T: Do the Costs of AUD-Related Health and Social Care Services Vary Across Patient Profiles? J Stud Alcohol Drugs. 2020 Mar;81(2):144-151.

Care outcomes and alcohol-related treatment utilisation profiles of patients with alcohol-use disorder: A prospective cohort study using electronic health records. Rautiainen, E., Ryynänen, O.P. & Laatikainen, T. Nordic Studies on Alcohol and Drugs, 1–15. Online first 5 Sep 2018.

Alcohol-related social and health service use patterns as predictors of death and remission in patients with AUD. Elina Rautiainen, Olli-Pekka Ryynänen, Eeva Reissell, Jussi Kauhanen, Tiina Laatikainen. Journal of Substance Abuse Treatment. Online 31st October 2018.

Rautiainen E, Linna M, Ryynänen O-P, Laatikainen T. Do the Costs of AUD-Related Health and Social Care Services Vary Across Patient Profiles? J Stud Alcohol Drugs. 2020 Mar;81(2):144-151.

Rautiainen E, Ryynänen O-P, Laatikainen T & Kekolahti P. (2020) Factors associated with the five-year costs of care among a cohort of alcohol use disorder patients: a Bayesian network model for examination of the causal effect of AUD remission to patients’ status and associated costs. Healthcare Informatics Research, 26(2): 129-145.

Rautiainen, E, Ryynänen, O-P, Rautiainen P, Laatikainen T. How do individuals with alcohol problems use social and healthcare services in Finland? Comparison of service use patterns between two high-need patient groups. Nordic Studies on Alcohol and Drugs 2021;38: 5: 450-465.

Presentations

Health research in progress II -research seminar, Joensuu, Finland 2019.

Geospatial Health as Interdisciplinary Research for Health Care Reform and Planning. Markku Tykkyläinen, Mikko Pyykönen, Sami Sieranoja, Pasi Fränti, Tiina Laatikainen. AAG 2019

Efficient allocation of health care service delivery using geospatial analysis and optimization at a regional level. Markku Tykkyläinen, Maija Toivakka, Aapeli Leminen, Teppo Repo, Tiina Laatikainen. AAG 2018.

Integration of health and social care – predicting the quality, costs and consequences 17.4.2018. Kick-off seminar of the STN IMPRO -project.

Christmas seminar on geoinformation and health services 19.12.2018

Hörhammer, Iiris, Linna, Miika ja Oksman, E. (2018). 8-Year Follow-up of a Health Coaching Intervention Effects on Health and Social Care Service Use, Cost of Care and Clinical Endpoints. World Congress of Cardiology & Cardiovascular Health, Dubai.